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Are nicotine-free e-liquids safe? What’s really in a 0mg bottle

Zero nicotine

Take the nicotine out of an e-liquid and you are left with three things: propylene glycol, vegetable glycerine and flavouring. This guide explains what each one is, what the named UK sources say about breathing them in, and what “no nicotine” does and doesn’t change.

Nicotine-free e-liquid bottles on a plain background

Only got a minute?
  • A 0mg e-liquid is PG, VG and flavouring, nothing else. The only thing missing compared with a 10ml nic salt is the nicotine.
  • Nobody can call it “safe” and neither can we. The NHS says vaping is not completely harmless and that the long-term effects are not yet known, and that applies whether or not the bottle has nicotine in it.
  • Removing nicotine removes the addictive ingredient, and Cancer Research UK states that nicotine itself does not cause cancer. It does not remove the fact that you are inhaling a heated aerosol.
  • Nicotine-containing e-liquids must be notified to the MHRA with a full ingredient list; 0mg liquids are not covered by that scheme. That is a real difference, and it makes the brand you buy from matter more, not less.
  • A retailer cannot answer a medical question. If you have one, ask your GP, a pharmacist or your local NHS stop smoking service, not a vape shop.

Inside a nicotine-free e-liquid

Every e-liquid on our shelves, from a 10ml bottle of 20mg salt to a Kingston 500ml, is built from the same short list of ingredients. Nicotine is an optional fourth. Take it out and you have a 0mg liquid, which is what a shortfill is before you add a nic shot. For a fuller breakdown of how the liquids, kits and coils fit together, our complete guide to e-cigarettes and e-liquids covers it end to end.

Propylene glycol (PG)
A thin, clear liquid that carries flavour and gives the throat hit. It is used widely in food, medicines and cosmetics. In e-liquid it is usually 30% to 50% of the bottle.
Vegetable glycerine (VG)
A thick, slightly sweet liquid that makes the vapour. Also a common food and pharmaceutical ingredient. Shortfills are typically around 70% VG; 10ml bottles are usually closer to a 50/50 mix.
Flavouring
Food-grade concentrates, usually a few percent of the mix. This is the part that varies most between brands and the part that regulators pay the most attention to.

An e-liquid is heated to a vapour, not burnt. That is a description of the process, not a health verdict, and the two should not be confused.

So is 0mg safe? The named sources in their own words

The honest answer is that no UK health body describes any e-liquid as safe, and we won’t either. What they do say is specific and worth reading properly.

The NHS, on its Better Health vaping page, states that vaping is not completely harmless and that it is not yet known what the long-term effects may be. Nothing in that statement hinges on nicotine. The uncertainty is about breathing in heated PG, VG and flavouring over years, and that uncertainty is the same at 0mg as at 20mg.

Cancer Research UK states that “nicotine makes cigarettes addictive. But nicotine itself doesn’t cause cancer.” That matters for this question in an unexpected way: it means removing nicotine does not remove the ingredient most people assume is the problem. What it removes is the addictive component.

Cancer Research UK also says “there is no good evidence that vaping causes cancer” while making clear that “e-cigarettes are not risk-free, and we don’t yet know their long-term effects.” It also says plainly that “if you have never smoked, you shouldn’t use e-cigarettes.” That advice is not conditional on nicotine strength.

The MHRA, the UK medicines regulator, requires every nicotine-containing e-liquid to be notified with a full ingredient list before it can be sold, and the regulations prohibit whole categories of additive; MHRA guidance treats diacetyl, the flavouring associated with the “popcorn lung” scare, as unacceptable, so UK-notified nicotine liquids do not contain it. The catch for this article is that those rules apply to liquids that contain nicotine. A 0mg liquid falls under general product safety law instead, with no notification requirement. A manufacturer may make its 0mg liquids to the same recipes and standards as its nicotine versions, but that is the manufacturer’s choice rather than a legal guarantee, so it is worth checking what the label tells you.

3
ingredients in a 0mg e-liquid: PG, VG, flavouring
0mg
the only strength legal above 10ml per bottle
18+
our minimum age for every vaping product, nicotine or not

What “no nicotine” changes, and what it doesn’t

Consideration With nicotine 0mg
Addictive ingredient Yes, nicotine None
Inhaling heated PG, VG and flavouring Yes Yes, unchanged
Long-term evidence Not yet known (NHS) The same flavourings; long-term inhalation data is limited (CRUK)
Throat hit Stronger, scales with mg Softer; comes from PG only
Bottle size allowed 10ml maximum Any size, 50ml to 500ml common
Age of sale 18+ by law 18+ here; the Tobacco and Vapes Act 2026 extends the age-of-sale rules to nicotine-free vapes
Vaping Products Duty from 1 October 2026 £2.20 per 10ml plus VAT Same rate; duty applies to all vaping liquid

One thing people are often surprised by: the new vape duty is charged on every millilitre of vaping liquid whether or not it contains nicotine, so 0mg shortfills are taxed too.

The “it’s just food ingredients” argument, and why it is only half right

PG and VG are both approved for use in food and medicines, and that gets quoted a lot as if it settles the matter. It doesn’t, for a simple reason: approval for swallowing something is not the same as evidence about breathing it in as a heated aerosol many times a day, and that inhalation evidence is still being gathered.

Flavourings are the part of the mix with the least long-term inhalation data. For nicotine-containing liquids the UK rules go some way to addressing that by prohibiting categories of additive, and a 0mg bottle depends on the manufacturer applying the same standards. What the rules cannot do is tell you that a given flavour molecule is harmless over twenty years, because nobody has that data yet for most of them. Cancer Research UK’s line, that “vapes haven’t been around for long enough to be sure”, is the fairest summary available.

The honest framing is that 0mg removes the nicotine and leaves the other open questions where they were.

Signature 50ml shortfill e-liquid, nicotine-free until a nic shot is added

Who buys nicotine-free e-liquid

There are broadly four groups, and each has a different reason to read the section above carefully.

Vapers who want a 0mg version of a flavour they already use. Most brands sell the same recipe across their strengths, including 0mg. Our guide to how nicotine strengths are labelled explains what the numbers mean. Any decision to change or reduce nicotine intake is a clinical question, not a retail one.

Shortfill users mixing their own strength. Every 50ml or 100ml shortfill is a 0mg liquid until you add a nic shot. If you are choosing between formats, shortfill vs 10ml walks through it.

Flavour chasers on sub-ohm kits. High-power direct-to-lung vaping on a box mod gets through a lot of liquid quickly and is run at low strengths, with 0mg and 3mg the usual labels on shortfill-based mixes. See MTL vs DTL if you are not sure which side of that line you sit on.

People who have never smoked and are curious. This is the group both the NHS and Cancer Research UK are addressing when they say never-smokers should not vape. A 0mg liquid does not change that advice, and we would rather lose the sale than pretend otherwise.

Choosing and using a 0mg liquid sensibly

  1. 1
    Buy from a UK brand with a UK ingredient declaration. Ranges such as Kingston, Hangsen and IVG sell 0mg options alongside their nicotine ranges. Check that the bottle you are buying carries an ingredient list, a batch number and the manufacturer’s details; a bottle with none of those is the one to avoid.
  2. 2
    Match the VG ratio to your kit. A 70/30 shortfill will struggle in a tight pod kit and burn coils. 50/50 suits MTL coils of 0.6 ohm and above (typically 0.6 to 1.2 ohm); high-VG 70/30 suits coils below about 0.6 ohm. A burnt coil is a common reason for a harsh vape.
  3. 3
    Don’t chase the missing throat hit with power. A common mistake when moving to 0mg is cranking the wattage to “feel” something. That heats the liquid harder, which is the opposite of what you want. Our list of common vaping mistakes covers this and others.
  4. 4
    Store it like any other e-liquid. Cool, dark, capped. 0mg liquid has no nicotine to oxidise, but flavourings still fade and VG still thickens. How long e-liquid lasts explains the signs of a bottle past its best.
  5. 5
    Pick flavours you already know. Most 0mg options are the same recipes as the nicotine versions, so start from a flavour you like. Our fruit e-liquid buying guide and longfill e-liquid guide cover the main routes to a 0mg or low-strength mix.

Read next

Understand strengths, formats and storage before you choose

These guides are information for adults who already vape. Our delivery and returns page (free UK delivery over £15) and rewards page (1.8 reward points on every £1) cover how the shop works.

Quick answers

Is nicotine-free e-liquid completely safe?

No. A 0mg liquid removes nicotine; it does not remove the heated PG, VG and flavouring you inhale, and the long-term questions about those are the same at every strength.

Is 0mg e-liquid addictive?

It contains no nicotine, which is the addictive ingredient in e-liquid.

Can I buy 0mg e-liquid if I am under 18?

No. We do not sell any vaping product, including 0mg, to anyone under 18, and the Tobacco and Vapes Act 2026 extends the legal age-of-sale rules to nicotine-free vapes. We verify age on every order.

Does the vape tax apply to nicotine-free liquid?

Yes. Vaping Products Duty from 1 October 2026 is £2.20 per 10ml plus VAT on all vaping liquid, with or without nicotine. Pre-duty stock can be sold until 31 March 2027.

Why does 0mg feel weaker or harsher than my usual liquid?

Nicotine provides much of the throat hit, so 0mg feels softer. If it feels harsh instead, the usual cause is a worn coil or too much power for the liquid, not the liquid itself.

Can I mix a 0mg shortfill with a nic shot?

Yes, that is what shortfills are designed for: a 0mg bottle with space left for a 10ml nicotine shot. Once the shot goes in the liquid is no longer nicotine-free, so write the final strength on the bottle and store it with the same care as any nicotine liquid.

Statements from the NHS, Cancer Research UK and the MHRA are taken from their published guidance at the time of writing and may be updated. This article is general product information, not medical advice. Vaping products are consumer products, not licensed medicines; speak to your GP, pharmacist or local NHS stop smoking service for medical questions. For adult smokers and vapers aged 18+ only.

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